GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7951870 | 1 | rs61882701 | chr11:46443275 | PACSIN3 | chr11:47199085-47207958:- | 0.18 | 4.1 | 4.93E-5 | Schizophrenia |
| THCA | cis | rs7951870 | 1 | rs61882710 | chr11:46473942 | PACSIN3 | chr11:47199085-47207958:- | 0.16 | 3.4 | 0.000728 | Schizophrenia |
| THCA | cis | rs7951870 | 1 | rs61882712 | chr11:46483948 | PACSIN3 | chr11:47199085-47207958:- | 0.16 | 3.4 | 0.000722 | Schizophrenia |
| THCA | cis | rs7951870 | 1 | rs61882746 | chr11:46567475 | PACSIN3 | chr11:47199085-47207958:- | 0.17 | 3.86 | 0.000128 | Schizophrenia |
| THCA | cis | rs7951870 | 1 | rs61882750 | chr11:46584227 | PACSIN3 | chr11:47199085-47207958:- | 0.16 | 3.59 | 0.000359 | Schizophrenia |
| THCA | cis | rs7951870 | 1 | rs61882758 | chr11:46611805 | PACSIN3 | chr11:47199085-47207958:- | 0.18 | 3.97 | 8.24E-5 | Schizophrenia |
| THCA | cis | rs7951870 | 1 | rs61884262 | chr11:46631299 | PACSIN3 | chr11:47199085-47207958:- | 0.18 | 4.13 | 4.22E-5 | Schizophrenia |
| THCA | cis | rs7951870 | 1 | rs61884264 | chr11:46639582 | PACSIN3 | chr11:47199085-47207958:- | 0.17 | 3.86 | 0.000131 | Schizophrenia |
| THCA | cis | rs11603691 | 1 | rs61888887 | chr11:57099051 | TIMM10 | chr11:57295936-57298232:- | -0.23 | -4.19 | 3.34E-5 | Low high density lipoprotein cholesterol levels |
| THCA | cis | rs17197710 | 1 | rs61897851 | chr11:47201981 | MADD | chr11:47290927-47351582:+ | 0.28 | 3.4 | 0.000734 | Waist-to-hip ratio adjusted for body mass index |
| THCA | cis | rs17197710 | 1 | rs61897852 | chr11:47203155 | MADD | chr11:47290927-47351582:+ | 0.28 | 3.44 | 0.00063 | Waist-to-hip ratio adjusted for body mass index |
| THCA | cis | rs10899021 | 1 | rs61900635 | chr11:74359010 | POLD3 | chr11:74303629-74353765:+ | -0.24 | -3.92 | 0.000101 | Response to metformin (IC50) |
| THCA | cis | rs10899021 | 1 | rs61900636 | chr11:74359591 | POLD3 | chr11:74303629-74353765:+ | -0.24 | -3.86 | 0.000131 | Response to metformin (IC50) |
| THCA | cis | rs983392 | 1 | rs61901691 | chr11:59902799 | MS4A14 | chr11:60145958-60185226:+ | 0.18 | 4.47 | 9.6E-6 | Alzheimer's disease (late onset) |
| THCA | cis | rs10862219 | 1 | rs61934658 | chr12:81445968 | ACSS3 | chr12:81471809-81649582:+ | 0.22 | 4.67 | 4.01E-6 | Neuroticism |